The HPE ProLiant DL380 Gen10 Plus Server (Part Number: P55247-B21) is a powerful and versatile 2U rack-mount enterprise server engineered to deliver exceptional performance, scalability, and reliability for modern data center environments. Built to support virtualization, software-defined storage, database management, hybrid cloud infrastructure, and mission-critical enterprise applications, this configuration provides a balanced combination of compute power, flexible storage, and advanced security features.
At the core of this server is the Intel Xeon Silver 4314 Processor, operating at up to 2.4 GHz with 16 physical cores. As part of Intel’s 3rd Generation Xeon Scalable family, this processor is designed to handle demanding workloads while maintaining strong energy efficiency. The 16-core architecture enables high levels of parallel processing, making the server ideal for virtualization environments where multiple virtual machines run simultaneously. It also performs efficiently in database applications, ERP systems, analytics workloads, and containerized environments. With advanced technologies such as Intel Turbo Boost and enhanced cache architecture, the Xeon Silver 4314 ensures consistent throughput and dependable performance under sustained loads.
The server comes equipped with 32GB DDR4 Registered (RDIMM) memory, delivering reliable and responsive system performance. DDR4 SmartMemory enhances bandwidth and reduces latency, helping ensure stable operations across enterprise workloads. One of the standout features of this model is its scalability—supporting memory expansion up to 2TB or more, depending on configuration. This high memory ceiling allows organizations to scale as business needs grow, whether expanding virtualization clusters or supporting memory-intensive analytics platforms. The inclusion of error-correcting code (ECC) technology further protects data integrity by detecting and correcting memory errors in real time.
Designed in a 2U rack form factor, the DL380 Gen10 Plus strikes a perfect balance between density and expandability. Its rack-optimized design makes it suitable for data centers that require efficient space utilization without compromising performance. The chassis layout is engineered for optimal airflow and cooling, ensuring stable operation even in high-demand environments. The modular internal design simplifies maintenance and upgrades, allowing IT administrators to install additional drives, memory modules, or expansion cards with minimal downtime.
Storage flexibility is another key strength of this configuration. The server supports 8 Small Form Factor (SFF) 2.5-inch drive bays, compatible with SAS, SATA, SSD, and NVMe drives. This versatility enables businesses to configure storage according to performance and capacity requirements. For high-speed applications requiring low latency and fast data access, NVMe SSDs provide exceptional throughput. For large data repositories and backup storage, SAS or SATA drives offer reliable and cost-effective solutions. This hybrid storage capability makes the DL380 Gen10 Plus suitable for both performance-driven and capacity-focused deployments.
To ensure optimal storage performance and data protection, this server includes the HPE MR416i-p Gen10 Plus RAID Controller. This advanced controller supports multiple RAID levels, providing redundancy, improved read/write performance, and enhanced fault tolerance. RAID configurations help protect critical data against drive failures, minimizing downtime and maintaining business continuity. The controller’s cache functionality further accelerates data processing and enhances overall storage efficiency.
Power reliability is equally robust. The server features an 800W Hot-Plug Redundant Power Supply, designed to deliver consistent and efficient power distribution. The hot-plug capability allows for power supply replacement without shutting down the system, ensuring maximum uptime for mission-critical applications. Redundant power options provide added protection against unexpected power failures, making this server highly suitable for enterprise environments where continuous availability is essential.
Beyond hardware performance, the DL380 Gen10 Plus incorporates advanced management and security technologies. HPE’s integrated management tools enable remote monitoring, configuration, and troubleshooting, reducing operational complexity for IT teams. Security features such as firmware protection and hardware-level safeguards help protect against cyber threats and unauthorized access, ensuring that sensitive business data remains secure.
This server is well-suited for a wide range of enterprise use cases, including virtualization clusters, private and hybrid cloud deployments, database hosting, enterprise resource planning systems, and high-performance storage environments. Its combination of multi-core processing power, scalable memory, flexible storage architecture, and redundant power design ensures that it can adapt to evolving IT demands.
In summary, the HPE ProLiant DL380 Gen10 Plus – P55247-B21 is a reliable, scalable, and high-performance server platform built to support modern enterprise workloads. With its Intel Xeon Silver 4314 16-core processor, 32GB expandable DDR4 memory, versatile 8-bay SFF storage support, MR416i-p RAID controller, and 800W hot-plug redundant power supply, this server provides the performance, flexibility, and resilience required for today’s data-driven organizations. It represents a strong investment for businesses seeking long-term reliability, operational efficiency, and future-ready infrastructure.


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